Animal Emergency Clinic, P.C.

(402) 339-6232

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Blood Distribution Center

Component Guidelines

CANINE COMPONENT THERAPY GUIDELINES
INDICATIONS RECOMMENDED COMPONENT
(In Order of Preference)  
 Anemia


1. Packed Red Blood Cells

2. Fresh Whole Blood

3. Stored Whole Blood

Massive Hemorrhage


1. Fresh Whole Blood

2. Fresh Frozen Plasma + Packed Red Cells

 Anticoagulant Toxicity  


1. Frozen Plasma

2. Fresh Frozen Plasma

3. High vWF Fresh Frozen Plasma

4. Fresh Whole Blood

 Hemophilia A


1. Cryoprecipitate

2. Fresh Frozen Plasma

3. High vWF Fresh Frozen Plasma

4. Fresh Whole Blood

 Hemophilia B


1. Frozen Plasma

2. Fresh Frozen Plasma

3. High vWF Fresh Frozen Plasma

4. Fresh Whole Blood

 vWD
1a. Cryoprecipitate
1b. High vWF Fresh Frozen Plasma
2. Fresh Frozen Plasma
3. Fresh Whole Blood
 
Thrombocytopenia
(Due to Marrow Disorder)
 1a.  Platelet Concentrate
1b.  Platelet Rich Plasma
1.  Fresh Whole Blood
 
DIC


1. Fresh Frozen Plasma

2. High vWF Fresh Frozen Plasma

3. Cryoprecipitate

4. Fresh Whole Blood

 Hypoproteinemia


1. Artificial Colloid

2. Frozen Plasma

3. Fresh Frozen Plasma

4. Fresh Whole Blood


CANINE DOSAGE & RATE CHART
Initial Rate is slow, starting with 1-3 ml over the first 5 minutes to observe for any transfusion reactions.
 
 PRODUCT DOSE   RATE
pRBCs
  6-10 ml/kg  Max rate 6-10 ml/kg/hr
 WHOLE BLOOD
 13-22 ml/kg   3-4ml/kg/hr
 FFP/FP/High vWF FFP
  6-10 ml/kg  Max rate 6-10 ml/kg/hr
 CRYOPRECIPITATE
  one unit per 10kg body weight  Max rate 6-10 ml/kg/hr

Note:Transfusion duration must not exceed 4 hours.
If given pre-surgically, cryoprecipitate & High vWF FFP should be given approximately 30 minutes before surgery.

As a dedicated team our priority is to provide professional, compassionate, and innovative emergency care for you and your pet.